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Antipsychotic metabolic monitoring checklist

ADA/APA metabolic monitoring standard for adults on second-generation antipsychotics: baseline, monthly, quarterly, and annual measurements.

Current version: v1.2 Updated: 2026-07-15 Reviewed by Shariq Refai, MD, MBA Audience: public + clinicians

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Version-locked PDF. When we revise this reference, the URL you're on stays the same and the file below is replaced with the current version. Link to this page (not to the file) so readers always receive the current version.

Download v1.2 PDF Filename: antipsychotic-cpz-equivalents.pdf

Overview

The 2004 ADA/APA consensus statement on metabolic monitoring for patients on second-generation antipsychotics remains the reference standard. This checklist condenses baseline, follow-up, and annual monitoring into a single page a prescriber can carry.

Contents

  • Baseline measurements before starting a second-generation antipsychotic
  • Weight and waist circumference cadence (12-week and quarterly checks)
  • Fasting glucose and lipid panel cadence (12-week and annual)
  • Blood pressure cadence
  • When to consult primary care or endocrinology for co-management

Sources

  • American Diabetes Association, American Psychiatric Association, American Association of Clinical Endocrinologists, North American Association for the Study of Obesity. Consensus development conference on antipsychotic drugs and obesity and diabetes. Diabetes Care 2004; 27(2):596-601.
  • Correll CU, Detraux J, De Lepeleire J, De Hert M. Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases. World Psychiatry 2015; 14(2):119-136.
  • FDA prescribing information for each second-generation antipsychotic (accessed via DailyMed).

Review record

  • Reviewer of record: Shariq Refai, MD, MBA (psychiatrist)
  • Current version: v1.2
  • Version updated: 2026-07-15
  • Next scheduled review: July 2027
  • Correction mechanism: /corrections-policy — email [email protected] with a specific source citation and we will review within two business weeks.

Canonical concepts

This reference maps to the following canonical Shrink Network concept ids: antipsychotic.

Related resources on PsychiatryRx

How to cite or link to this reference

If you're referencing this in a syllabus, institutional protocol, or academic material:

Antipsychotic metabolic monitoring checklist (v1.2, updated 2026-07-15). PsychiatryRx. https://psychiatryrx.org/references/antipsychotic-metabolic-monitoring. Reviewed by Shariq Refai, MD, MBA.

Link to the URL above, not the PDF file. That way your readers receive the current version even after we revise.